For (1) you have \(\displaystyle \int 2^x\sqrt{4x+ 2^{x+ 1}+ 5} dx\) (Though you forgot the "dx". That's important.)
That is extremely difficult and may, in fact, not have an "elementary" integral. But if you meant
\(\displaystyle \int 2^x\sqrt{4^x+ 2^{x+ 1}+ 5}dx\)
that's much easier. \(\displaystyle 4^x= (2^2)^x= (2^x)^2\) and \(\displaystyle 2^{x+ 1}=2(2^x)\). Use the substitution \(\displaystyle u= 2^x\)