probability, permutations, and combinations

How many ways can you arrange 3 quarters and 7 nickels in a line? 3,628,800
Please show us what you have tried and exactly where you are stuck.

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How many ways can you arrange 3 quarters and 7 nickels in a line? 3,628,800
The letters in the word MISSISSIPPIMISSISSIPPI can be arranged in 11!(4!)2(2!)\dfrac{11!}{(4!)^2(2!)} ways.
How any can you arrange the string QQQNNNNNNN ?QQQNNNNNNN~?
 
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